Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983600 | 0.92 | MAPT (0.40) | PKMTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL7411038 | 0.87 | PKM (0.43) | PKMTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL6985749 | 0.87 | ALDH1A1 (0.48) | PKMTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL6985322 | 0.85 | GAA (0.41) | PKMTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL6978509 | 0.84 | PTGER4 (0.40) | ALDH1A1MEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL6977498 | 0.84 | CCKBR (0.44) | PKMTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL6984039 | 0.84 | TP53 (0.45) | PKMTP53ALDH1A1KDM4EMAPT | |
| SCHEMBL6984851 | 0.83 | BRD4 (0.50) | PKMTP53MEN1KMT2AMAPT | |
| SCHEMBL7408050 | 0.83 | TP53 (0.40) | PKMTP53ALDH1A1MEN1HPGD | |
| SCHEMBL6982764 | 0.83 | FPR1 (0.43) | PKMALDH1A1MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |