Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984759 | 0.92 | LMNA (0.47) | TP53LMNAPKMMAPTTHRB | |
| SCHEMBL6985322 | 0.91 | GAA (0.41) | TP53LMNAPKMMAPTTHRB | |
| SCHEMBL6977498 | 0.90 | CCKBR (0.44) | TP53LMNAPKMMAPTTHRB | |
| SCHEMBL7411038 | 0.90 | PKM (0.43) | TP53LMNAPKMMAPTTHRB | |
| SCHEMBL6978217 | 0.89 | SLC16A3 (0.42) | TP53LMNAPKMMAPTCNR1 | |
| SCHEMBL6982953 | 0.89 | CCR10 (0.39) | TP53LMNAPKMMAPTCNR1 | |
| SCHEMBL6985343 | 0.88 | LMNA (0.51) | LMNAPKMNR3C1ALDH1A1GAA | |
| SCHEMBL6982163 | 0.88 | SLC16A3 (0.45) | TP53LMNAPKMMAPTTHRB | |
| SCHEMBL6982764 | 0.87 | FPR1 (0.43) | LMNAPKMMAPTNR3C1KDM4E | |
| SCHEMBL6985749 | 0.87 | ALDH1A1 (0.48) | TP53LMNAPKMMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |