Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403770 | 0.87 | L3MBTL1 (0.67) | SIGMAR1MEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL7414475 | 0.85 | KDM4E (0.60) | SIGMAR1MEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL7412504 | 0.84 | GAA (0.57) | MEN1KMT2AL3MBTL1EPHX2ALDH1A1 | |
| SCHEMBL8066357 | 0.83 | GAA (0.59) | MEN1KMT2AL3MBTL1EPHX2ALDH1A1 | |
| SCHEMBL8188060 | 0.82 | KMT2A (0.47) | SIGMAR1MEN1KMT2AL3MBTL1EPHX2 | |
| SCHEMBL7412108 | 0.81 | POLB (0.55) | SIGMAR1MEN1KMT2AL3MBTL1EPHX2 | |
| SCHEMBL8329590 | 0.78 | FAAH (0.49) | SIGMAR1MEN1KMT2AFAAHALDH1A1 | |
| SCHEMBL8186034 | 0.75 | FAAH (0.46) | SIGMAR1MEN1KMT2AFAAHALDH1A1 | |
| SCHEMBL12489580 | 0.74 | ALDH1A1 (0.68) | L3MBTL1TACR3ALDH1A1POLBHDAC8 | |
| SCHEMBL16973965 | 0.74 | ALDH1A1 (0.68) | L3MBTL1TACR3ALDH1A1POLBHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117840-A | INHIBITS BINDING BETWEEN VLA-4 RECEPTOR EXPRESSED ON INFLAMMATORY LEUKOCYTES AND FIBRONECTIN CS-1 PEPTIDE EXPRESSED ON ENDOTHELIAL CELLS THAT ARE INVOLVED IN IMMUNOINFLAMMATORY DISEASE STATES | CYTEL CORPORATION (US) | 2000-09-12 | — | — | US | disclosed |
| US-6103870-A | INHIBITS BINDING BETWEEN VLA-4 RECEPTOR EXPRESSED ON INFLAMMATORY LEUKOCYTES AND FIBRONECTIN CS-1 PEPTIDE EXPRESSED ON ENDOTHELIAL CELLS; ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS; TREATMENT OF ASTHMA | CYTEL CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
| WO-2000002903-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 2000-01-20 | — | — | WO | disclosed |
| US-5936065-A | PRODRUG AS ANTIINFLAMMATORY AGENT FOR AUTOIMMUNE DISEASES; FOR SUPPRESSING BINDING OF INFLAMMATORY CELLS TO ENDOTHELIAL CELLS THAT EXPRESS THE CS-1 PORTION OF FIBRONECTIN ON THEIR SURFACES | CYTEL CORPORATION (US) | 1999-08-10 | — | — | US | disclosed |
| US-5770573-A | CS-1 peptidomimetics, compositions and methods of using the same | CYTEL CORPORATION (US) | 1998-06-23 | — | — | US | disclosed |
| US-5688913-A | OLIGOPEPTIDES AS ANTIINFLAMMATORY AGENTS | CYTEL CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |