Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412504 | 0.83 | GAA (0.57) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8186034 | 0.82 | FAAH (0.46) | FAAHALDH1A1KDM4EHSD11B1MAPT | |
| SCHEMBL8066357 | 0.82 | GAA (0.59) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7412108 | 0.79 | POLB (0.55) | ALDH1A1KDM4EHSD11B1MAPTSIGMAR1 | |
| SCHEMBL7108356 | 0.79 | KDM4E (0.74) | ALDH1A1KDM4EMEN1KMT2AHTR1A | |
| SCHEMBL7414197 | 0.78 | SIGMAR1 (0.50) | FAAHALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL7108298 | 0.78 | KDM4E (0.72) | ALDH1A1KDM4EMEN1KMT2AHTR1A | |
| SCHEMBL7412711 | 0.78 | NAMPT (0.48) | FAAHALDH1A1KDM4EMAPTHDAC8 | |
| SCHEMBL8403770 | 0.77 | L3MBTL1 (0.67) | FAAHALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL7414475 | 0.75 | KDM4E (0.60) | ALDH1A1KDM4EMAPTSIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737204-A4 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORP (US) | 1999-06-23 | — | — | EP | disclosed |
| EP-0737204-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995015973-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1995-06-15 | — | — | WO | disclosed |