Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403770 | 0.89 | L3MBTL1 (0.67) | SMN1; SMN2ALDH1A1L3MBTL1NPSR1KMT2A | |
| SCHEMBL7414197 | 0.85 | SIGMAR1 (0.50) | ALDH1A1L3MBTL1NPSR1KMT2AMEN1 | |
| SCHEMBL7412504 | 0.81 | GAA (0.57) | KDM4ESMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL8066357 | 0.80 | GAA (0.59) | KDM4ESMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL7412108 | 0.77 | POLB (0.55) | KDM4EALDH1A1GAAL3MBTL1KMT2A | |
| SCHEMBL17117483 | 0.76 | ALDH1A1 (0.66) | KDM4ESMN1; SMN2CYP2C19ALDH1A1GAA | |
| SCHEMBL8188060 | 0.76 | KMT2A (0.47) | ALDH1A1L3MBTL1KMT2APKMLMNA | |
| SCHEMBL8329590 | 0.75 | FAAH (0.49) | KDM4EALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL5369479 | 0.73 | POLB (0.78) | KDM4ESMN1; SMN2CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL5370503 | 0.73 | ALDH1A1 (0.77) | KDM4ESMN1; SMN2CYP2C19ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000002903-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 2000-01-20 | — | — | WO | disclosed |