Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414475 | 0.89 | KDM4E (0.60) | L3MBTL1RAB9ASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL7414197 | 0.87 | SIGMAR1 (0.50) | L3MBTL1POLBNPSR1MEN1KMT2A | |
| SCHEMBL7412504 | 0.83 | GAA (0.57) | L3MBTL1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8066357 | 0.82 | GAA (0.59) | L3MBTL1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7309037 | 0.80 | L3MBTL1 (1.00) | L3MBTL1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7412108 | 0.79 | POLB (0.55) | L3MBTL1POLBMEN1KMT2ASIGMAR1 | |
| SCHEMBL7303045 | 0.79 | NPSR1 (0.81) | L3MBTL1SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL8188060 | 0.78 | KMT2A (0.47) | L3MBTL1POLBMEN1KMT2ASIGMAR1 | |
| SCHEMBL8329590 | 0.77 | FAAH (0.49) | MEN1KMT2ASIGMAR1ALDH1A1FAAH | |
| SCHEMBL7313251 | 0.74 | KDM4E (0.77) | POLBRAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936065-A | PRODRUG AS ANTIINFLAMMATORY AGENT FOR AUTOIMMUNE DISEASES; FOR SUPPRESSING BINDING OF INFLAMMATORY CELLS TO ENDOTHELIAL CELLS THAT EXPRESS THE CS-1 PORTION OF FIBRONECTIN ON THEIR SURFACES | CYTEL CORPORATION (US) | 1999-08-10 | — | — | US | disclosed |
| US-5821231-A | TREATMENT OF IMMUNOINFLAMMATORY CONDITIONS | CYTEL CORPORATION (US) | 1998-10-13 | — | — | US | disclosed |
| US-5770573-A | CS-1 peptidomimetics, compositions and methods of using the same | CYTEL CORPORATION (US) | 1998-06-23 | — | — | US | disclosed |