Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 9/20 | 0.54 |
| ▸ | MMP1 | P03956 | 7/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762585 | 0.82 | MMP13 (0.51) | MMP13MMP1PKMMMP2MMP9 | |
| SCHEMBL9951983 | 0.81 | MMP13 (0.58) | MMP13MMP1PKMMMP2MMP9 | |
| SCHEMBL4195254 | 0.80 | PKM (0.61) | MMP13MMP1PKMMMP2MMP9 | |
| SCHEMBL7411621 | 0.77 | MMP13 (0.57) | MMP13MMP1PKMMMP2MMP9 | |
| SCHEMBL7352846 | 0.76 | MMP13 (0.60) | MMP13MMP1PKMMMP2MMP9 | |
| SCHEMBL9732631 | 0.75 | PKM (0.59) | MMP13MMP1PKMMMP2MMP9 | |
| SCHEMBL11575338 | 0.75 | PKM (0.59) | MMP13MMP1PKMMMP2MMP9 | |
| SCHEMBL751678 | 0.75 | PKM (0.59) | MMP13MMP1PKMMMP2MMP9 | |
| SCHEMBL6929276 | 0.74 | MMP1 (0.70) | MMP13MMP1PKMMMP2MMP9 | |
| SCHEMBL7207035 | 0.74 | MMP1 (0.54) | MMP13MMP1PKMMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927168-A1 | 1,3-DIHETEROCYCLIC METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998008822-A1 | 1,3-DIHETEROCYCLIC METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |