Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 10/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426906 | 0.93 | HDAC1 (0.37) | BCHEMEN1KMT2ATDP1HDAC1 | |
| SCHEMBL7417819 | 0.88 | HDAC1 (0.34) | BCHEMEN1KMT2ATDP1HDAC1 | |
| SCHEMBL7424802 | 0.84 | ALDH1A1 (0.36) | HDAC1HDAC6 | |
| SCHEMBL7424356 | 0.81 | HDAC1 (0.36) | BCHEKMT2AHDAC1HDAC6 | |
| SCHEMBL7425444 | 0.80 | NR4A2 (0.32) | — | |
| SCHEMBL7426729 | 0.80 | TP53 (0.39) | TP53 | |
| SCHEMBL7429286 | 0.79 | NR4A2 (0.31) | — | |
| SCHEMBL7382337 | 0.77 | MAPT (0.41) | TDP1 | |
| SCHEMBL7420456 | 0.76 | ADRB3 (0.35) | MEN1KMT2ALNPEP | |
| SCHEMBL7426234 | 0.75 | LOXL2 (0.47) | MEN1KMT2AHDAC1HDAC6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |