Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422281 | 0.88 | SHMT1 (0.39) | TP53MAPTLMNASHMT1SHMT2 | |
| SCHEMBL1655299 | 0.87 | ATM (0.46) | TP53POLBMAPTLMNASMN1; SMN2 | |
| SCHEMBL7425245 | 0.86 | HSD17B10 (0.39) | TP53MAPTLMNASHMT1SHMT2 | |
| SCHEMBL7426906 | 0.83 | HDAC1 (0.37) | — | |
| SCHEMBL7382337 | 0.83 | MAPT (0.41) | POLBMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7424802 | 0.80 | ALDH1A1 (0.36) | MAPTLMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7420766 | 0.80 | ALDH1A1 (0.47) | TP53POLBMAPTLMNASHMT1 | |
| SCHEMBL7423907 | 0.80 | SHMT1 (0.56) | MAPTSHMT1SHMT2SMN1; SMN2RAB9A | |
| SCHEMBL7423323 | 0.80 | BCHE (0.33) | TP53 | |
| SCHEMBL7422924 | 0.79 | PLA2G10 (0.53) | MAPTSHMT1SHMT2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |