Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 8/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415517 | 0.85 | DRD2 (0.43) | DRD2DRD4DRD3LMNA | |
| SCHEMBL4224097 | 0.79 | GPR119 (0.58) | TP53THRBMAPTGPR119STS | |
| SCHEMBL2897131 | 0.74 | TP53 (0.53) | TP53THRBMAPTGPR119LMNA | |
| SCHEMBL1789927 | 0.74 | DRD2 (0.57) | DRD2DRD4 | |
| SCHEMBL3570582 | 0.74 | ACHE (0.61) | TP53THRBMAPTGPR119STS | |
| SCHEMBL3779080 | 0.72 | CHRM4 (0.56) | TP53THRBMAPTGPR119STS | |
| SCHEMBL7849387 | 0.71 | GPR119 (0.55) | DRD2DRD4GPR119 | |
| Hydrochloric Acid SCHEMBL3966170 | 0.71 | CHRM4 (0.55) | TP53THRBMAPTGPR119STS | |
| SCHEMBL2862442 | 0.71 | ALDH1A1 (0.60) | TP53THRBMAPTLMNA | |
| SCHEMBL7848865 | 0.71 | CHRM4 (0.47) | TP53THRBMAPTGPR119PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |