Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281350 | 0.81 | OPRD1 (0.40) | CES2CES1DPP4 | |
| SCHEMBL15797633 | 0.81 | ALDH1A1 (0.42) | CES2CES1TEAD1NR1I2ALDH1A1 | |
| SCHEMBL7438870 | 0.78 | CHRM2 (0.44) | CHRM2CHRM1ALDH1A1 | |
| SCHEMBL7434817 | 0.78 | LMNA (0.51) | ALDH1A1 | |
| SCHEMBL7426489 | 0.78 | CHRM2 (0.38) | TEAD1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL7437442 | 0.76 | TSHR (0.45) | TEAD1CHRM2CHRM1 | |
| SCHEMBL7441378 | 0.76 | TEAD1 (0.54) | CES2CES1TEAD1SCN5ASCN9A | |
| SCHEMBL7440423 | 0.76 | PDE1A (0.40) | CHRM2CHRM1ALDH1A1 | |
| SCHEMBL7445606 | 0.74 | ADRA1D (0.41) | TRPM8ALDH1A1 | |
| SCHEMBL7445756 | 0.74 | CES2 (0.46) | CES2TEAD1CHRM2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |