SCHEMBL31069896

SCHEMBL31069896

BrCc1ccc(-c2ccccc2-c2ncon2)cc1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
CASP6 P55212 1/20 0.33
KMO O15229 1/20 0.33
PPARA Q07869 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
GP6 Q9HCN6 1/20 0.32
AGTR1 P30556 2/20 0.31
AGTR2 P50052 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31069897 1.00 TRPA1 (0.35) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL374649 0.83 KMO (0.37) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL17984215 0.81 GPR55 (0.47) ALDH1A1TSHRPPARAGPR55ADORA2A
SCHEMBL10892045 0.77 ALDH1A1 (0.57) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL9023806 0.73 ALDH1A1 (0.59) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL7427014 0.73 L3MBTL1 (0.45) ALDH1A1TSHRGPR55
SCHEMBL1949784 0.71 RAB9A (0.43) ALDH1A1TSHRCASP6PPARA
SCHEMBL1890535 0.70 GPR55 (0.38) ALDH1A1TSHRGPR55
Ammonia Solution, Strong SCHEMBL28198912 0.68 LTA4H (0.42) TRPA1ALDH1A1TSHRCES1GPR55
SCHEMBL5475553 0.67 CASP3 (0.52) ALDH1A1TSHRCASP6ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112898287-B Preparation method of azilsartan 江苏中邦制药有限公司 2024-08-30 CN claimed