Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 7/20 | 0.50 |
| ▸ | CTSS | P25774 | 6/20 | 0.50 |
| ▸ | CTSB | P07858 | 5/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP9 | P55211 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388307 | 0.96 | CTSK (0.51) | CASP3CASP7CTSKCTSSCTSB | |
| SCHEMBL8892749 | 0.91 | CTSK (0.55) | CTSKCTSSCTSBCTSLTGM2 | |
| SCHEMBL7432162 | 0.89 | CTSB (0.52) | CASP3CTSKCTSSCTSBREN | |
| SCHEMBL8893671 | 0.89 | CTSS (0.55) | CTSKCTSSCTSBCTSL | |
| SCHEMBL8895231 | 0.89 | CTSS (0.55) | CTSKCTSSCTSBCTSL | |
| SCHEMBL7438999 | 0.88 | CTSS (0.55) | CASP3CASP7CTSKCTSSCTSB | |
| SCHEMBL7391841 | 0.87 | CTSK (0.56) | CTSKCTSSCTSBCTSL | |
| SCHEMBL7439440 | 0.86 | CTSB (0.48) | CASP3CASP7CTSKCTSSCTSB | |
| SCHEMBL8892973 | 0.82 | CTSS (0.52) | CTSSCTSBCTSL | |
| SCHEMBL7428713 | 0.81 | CTSS (0.51) | CTSKCTSSCTSBCTSLCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |