Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.55 |
| ▸ | CTSK | P43235 | 10/20 | 0.54 |
| ▸ | CTSB | P07858 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895231 | 1.00 | CTSS (0.55) | CTSSCTSKCTSBCTSL | |
| SCHEMBL7388307 | 0.92 | CTSK (0.51) | CTSSCTSKCTSBCTSL | |
| SCHEMBL7438999 | 0.91 | CTSS (0.55) | CTSSCTSKCTSBCTSL | |
| SCHEMBL8893516 | 0.89 | CASP3 (0.51) | CTSSCTSKCTSBCTSL | |
| SCHEMBL7432162 | 0.84 | CTSB (0.52) | CTSSCTSKCTSBCTSL | |
| SCHEMBL7428713 | 0.83 | CTSS (0.51) | CTSSCTSKCTSBCTSL | |
| SCHEMBL7391841 | 0.81 | CTSK (0.56) | CTSSCTSKCTSBCTSL | |
| SCHEMBL7439440 | 0.81 | CTSB (0.48) | CTSSCTSKCTSBCTSL | |
| SCHEMBL27514276 | 0.80 | CCR1 (0.65) | CTSSCTSKCTSBCTSL | |
| SCHEMBL25285647 | 0.80 | CTSK (0.65) | CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |