Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 5/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437290 | 0.95 | PNMT (0.42) | DPP7NAMPTALDH1A1GLAPNMT | |
| SCHEMBL7440791 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BNAMPTALDH1A1MMP8 | |
| SCHEMBL7448788 | 0.76 | ALDH1A1 (0.42) | DPP7NAMPTALDH1A1GLASIGMAR1 | |
| SCHEMBL14558962 | 0.75 | DRD2 (0.54) | ALDH1A1SIGMAR1MAPTNPC1MAPK1 | |
| SCHEMBL7664159 | 0.74 | ALDH1A1 (0.42) | DPP7NAMPTALDH1A1GLASIGMAR1 | |
| SCHEMBL655730 | 0.74 | ALDH1A1 (0.44) | ALDH1A1GLAPNMTADRA2AADRA2B | |
| SCHEMBL655452 | 0.74 | ALDH1A1 (0.41) | ALDH1A1GLAPNMTADRA2AADRA2B | |
| SCHEMBL38658114 | 0.71 | DPP7 (0.51) | DPP7NAMPTALDH1A1GLASIGMAR1 | |
| SCHEMBL8699228 | 0.70 | SIRT2 (0.48) | ALDH1A1MAPTNPC1MAPK1RAB9A | |
| SCHEMBL7399767 | 0.69 | ALDH1A1 (0.40) | ITGB3ALDH1A1PNMTADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |