Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 11/20 | 0.50 |
| ▸ | CTSL | P07711 | 4/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276185 | 0.89 | CTSL (0.52) | RENCTSLCTSSCTSKCTSB | |
| SCHEMBL9011706 | 0.85 | CTSS (0.51) | RENCTSLCTSSCTSKCTSB | |
| SCHEMBL7329100 | 0.83 | CTSK (0.51) | RENCTSLCTSSCTSKCTSB | |
| SCHEMBL7434284 | 0.83 | CTSK (0.51) | RENCTSLCTSSCTSKCTSB | |
| SCHEMBL7429221 | 0.82 | CTSK (0.52) | RENCTSLCTSSCTSKCTSB | |
| SCHEMBL9012671 | 0.82 | REN (0.47) | RENCTSLCTSSCTSKPSEN1 | |
| SCHEMBL7294910 | 0.78 | CTSK (0.53) | RENCTSLCTSSCTSKCTSB | |
| SCHEMBL7278761 | 0.78 | REN (0.50) | RENCTSLCTSSCTSKCTSB | |
| SCHEMBL10445293 | 0.76 | REN (0.46) | RENCTSLCTSSCTSKCTSB | |
| SCHEMBL8372704 | 0.75 | CTSB (0.61) | RENCTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |