Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289950 | 0.85 | SLC6A2 (0.47) | NPSR1NOD2 | |
| SCHEMBL7435488 | 0.78 | CYP3A4 (0.36) | NPSR1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL7291944 | 0.76 | TSHR (0.56) | KDM4ENPSR1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7434230 | 0.75 | P2RX7 (0.38) | NPSR1ALDH1A1POLBL3MBTL1KMT2A | |
| SCHEMBL7444020 | 0.71 | L3MBTL1 (0.46) | KDM4EALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL7434817 | 0.70 | LMNA (0.51) | NPSR1ALDH1A1LMNAKMT2A | |
| SCHEMBL7438106 | 0.70 | GAA (0.34) | KDM4EALDH1A1POLBKMT2A | |
| SCHEMBL11847697 | 0.69 | HTR3E (0.43) | LMNA | |
| SCHEMBL7437442 | 0.69 | TSHR (0.45) | NPSR1LMNA | |
| SCHEMBL7439650 | 0.69 | CHRM2 (0.56) | KDM4EALDH1A1LMNAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |