SCHEMBL7435825

SCHEMBL7435825

CCN(CC)N1CC(=O)N(C(CS)Cc2ccccc2)C1=O

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CPA3 P15088 1/20 0.39
FOLH1 Q04609 1/20 0.39
MC4R P32245 1/20 0.37
ALDH1A1 P00352 1/20 0.35
PKM P14618 1/20 0.35
ACHE P22303 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
MME P08473 1/20 0.33
ANPEP P15144 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7440259 0.89 CPA3 (0.37) CPA3FOLH1ALDH1A1PKMTDP1
SCHEMBL7435805 0.80 CPA3 (0.38) CPA3FOLH1ALDH1A1PKMTDP1
SCHEMBL7435831 0.78 ACHE (0.40) MC4RALDH1A1ACHEMEN1KMT2A
SCHEMBL7432640 0.76 ENPP2 (0.47) CPA3FOLH1ALDH1A1PKMMEN1
SCHEMBL7445692 0.75 ENPP2 (0.36) CPA3FOLH1ALDH1A1PKMACHE
SCHEMBL7426791 0.74 CPA3 (0.38) CPA3FOLH1ALDH1A1PKMMEN1
SCHEMBL7446522 0.74 CPA3 (0.44) CPA3FOLH1ALDH1A1PKMMME
SCHEMBL7440464 0.74 FOLH1 (0.41) CPA3FOLH1ALDH1A1PKMMEN1
SCHEMBL7425886 0.73 HSD11B1 (0.44) CPA3FOLH1ALDH1A1PKMMEN1
SCHEMBL7428787 0.73 KMT2A (0.45) CPA3FOLH1ALDH1A1PKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640594-A1 Hydantoin derivative as metalloprotease inhibitor FUJIREBIO INC. (JP) 1995-03-01 EP disclosed