SCHEMBL7445692

SCHEMBL7445692

CC(C)(C)CN1CC(=O)N(C(CS)Cc2ccccc2)C1=O

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.36
CPA3 P15088 1/20 0.36
FOLH1 Q04609 1/20 0.36
ALDH1A1 P00352 1/20 0.35
PKM P14618 1/20 0.35
ACHE P22303 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MME P08473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7432640 0.84 ENPP2 (0.47) ENPP2CPA3FOLH1ALDH1A1PKM
SCHEMBL7428787 0.81 KMT2A (0.45) ENPP2CPA3FOLH1ALDH1A1PKM
SCHEMBL7428452 0.81 PLA2G10 (0.45) ENPP2CPA3FOLH1ALDH1A1PKM
SCHEMBL7426519 0.79 MME (0.42) ENPP2CPA3FOLH1ALDH1A1PKM
SCHEMBL7440464 0.79 FOLH1 (0.41) CPA3FOLH1ALDH1A1PKMHPGD
SCHEMBL7445702 0.78 ACHE (0.40) ENPP2ALDH1A1ACHEPOLBMEN1
SCHEMBL7435994 0.77 MME (0.41) ENPP2CPA3FOLH1ALDH1A1PKM
SCHEMBL7435805 0.77 CPA3 (0.38) CPA3FOLH1ALDH1A1PKMTDP1
SCHEMBL7440724 0.75 HRH4 (0.43) ENPP2ALDH1A1MEN1KMT2A
SCHEMBL7435825 0.75 CPA3 (0.39) CPA3FOLH1ALDH1A1PKMACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640594-A1 Hydantoin derivative as metalloprotease inhibitor FUJIREBIO INC. (JP) 1995-03-01 EP disclosed