Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 6/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444403 | 0.95 | BCHE (0.42) | ALDH1A1HPGDSMN1; SMN2BCHEPOLB | |
| SCHEMBL7313879 | 0.88 | ALDH1A1 (0.44) | ALDH1A1HPGDSMN1; SMN2PSMB5PSMB1 | |
| SCHEMBL7436647 | 0.88 | ALDH1A1 (0.44) | ALDH1A1HPGDSMN1; SMN2PSMB5PSMB1 | |
| SCHEMBL7301739 | 0.88 | ALDH1A1 (0.43) | ALDH1A1HPGDSMN1; SMN2POLBPSMB5 | |
| SCHEMBL7437241 | 0.87 | ALDH1A1 (0.39) | ALDH1A1HPGDSMN1; SMN2BCHEPOLB | |
| SCHEMBL7312132 | 0.86 | CTSG (0.43) | ALDH1A1HPGDSMN1; SMN2POLBPSMB5 | |
| SCHEMBL8680990 | 0.85 | ALDH1A1 (0.40) | ALDH1A1HPGDSMN1; SMN2POLBPSMB5 | |
| SCHEMBL7299047 | 0.84 | PSEN1 (0.44) | ALDH1A1HPGDSMN1; SMN2BCHEPSMB5 | |
| SCHEMBL7444412 | 0.84 | PSEN1 (0.44) | ALDH1A1HPGDSMN1; SMN2BCHEPSMB5 | |
| SCHEMBL7303357 | 0.82 | CTSS (0.46) | ALDH1A1POLBPSMB5PSMB1PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525420-B1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | MITSUBISHI CHEM CORP (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5834508-A | PROTEASE ENZYME INHIBITORS; MUSCLE DISORDERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |