Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442088 | 0.89 | TBXAS1 (0.38) | ALDH1A1 | |
| SCHEMBL7448248 | 0.87 | SMN1; SMN2 (0.35) | SCN1ASCN2ASCN3AL3MBTL1TSHR | |
| SCHEMBL7437146 | 0.84 | MEN1 (0.43) | L3MBTL1TSHRCYP3A4ALDH1A1KDM4E | |
| SCHEMBL9134829 | 0.83 | L3MBTL1 (0.41) | SCN1ASCN2ASCN3AL3MBTL1TSHR | |
| SCHEMBL7436705 | 0.80 | L3MBTL1 (0.37) | L3MBTL1TSHRCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7442500 | 0.79 | TRPA1 (0.34) | TSHRALDH1A1GLAHPGDKDM4E | |
| SCHEMBL7444181 | 0.78 | TSHR (0.38) | L3MBTL1TSHRCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9131964 | 0.77 | ALDH1A1 (0.37) | CYP2D6ALDH1A1GLAHPGDKDM4E | |
| SCHEMBL7439021 | 0.74 | SCN1A (0.36) | SCN1ASCN2ASCN3ATSHRCYP2D6 | |
| SCHEMBL9130638 | 0.74 | PPM1D (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491149-A | VIRICIDES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |