Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434800 | 0.88 | SLC9A1 (0.41) | MAPTALDH1A1SLC9A1 | |
| SCHEMBL7440169 | 0.87 | SLC9A1 (0.41) | MAPTKDM4EKMT2AALDH1A1SLC9A1 | |
| SCHEMBL7440591 | 0.84 | ALPL (0.35) | MAPTALDH1A1SLC9A1LMNA | |
| SCHEMBL7439224 | 0.76 | ATP4A (0.37) | MAPTKDM4EKMT2AALDH1A1PDGFRB | |
| SCHEMBL4243696 | 0.73 | MAP2K3 (0.47) | MAPTKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL14736658 | 0.71 | ADORA3 (0.40) | MAPTKDM4EKMT2AALDH1A1PDGFRB | |
| SCHEMBL9521709 | 0.70 | ALDH1A1 (0.41) | MAPTKDM4EKMT2AALDH1A1PDGFRB | |
| SCHEMBL21336547 | 0.70 | MEN1 (0.38) | MAPTKDM4EKMT2AALDH1A1PDGFRB | |
| SCHEMBL7426992 | 0.69 | BPTF (0.36) | KDM4EKMT2AALDH1A1PDGFRBSLC9A1 | |
| SCHEMBL9324010 | 0.69 | TP53 (0.44) | KDM4EKMT2AALDH1A1PDGFRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506194-B1 | 4-aryl-thiazole or imidazole derivatives | AKZO NOBEL NV (NL) | 1996-08-21 | — | — | EP | disclosed |
| US-5254575-A | 4-aryl-thiazole derivatives | AKZO N.V. (NL) | 1993-10-19 | — | — | US | disclosed |
| EP-0506194-A1 | 4-aryl-thiazole or imidazole derivatives | Akzo Nobel N.V. (NL) | 1992-09-30 | — | — | EP | disclosed |