Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442226 | 0.87 | FFAR1 (0.35) | RORCHSD17B10ALDH1A1SLC6A4CHRM2 | |
| SCHEMBL7435145 | 0.84 | KDM4E (0.35) | CTSDBACE1KDM4ETSHRMAPK1 | |
| SCHEMBL10989168 | 0.82 | THRB (0.36) | PNMTITGB3ITGA2BCHRM2POLB | |
| SCHEMBL7440201 | 0.81 | ADRB2 (0.38) | KDM4EITGB3ITGA2BSLC6A4ITGAV | |
| SCHEMBL7435505 | 0.81 | PNMT (0.36) | PNMTKDM4ETSHRMAPK1HSD17B10 | |
| SCHEMBL7436499 | 0.80 | GNAI3 (0.30) | GNAI3GNAO1GNAI1 | |
| SCHEMBL7434523 | 0.80 | GNAI3 (0.31) | SLC6A4SLC6A2SLC6A3KCNH2GNAI3 | |
| SCHEMBL7433144 | 0.80 | ADRB2 (0.35) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL7440923 | 0.78 | THRA (0.37) | KDM4EITGB3ITGA2BSLC6A4ITGAV | |
| SCHEMBL7445248 | 0.78 | LMNA (0.33) | KDM4EALDH1A1CHRM2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |