Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.48 |
| ▸ | CTSS | P25774 | 12/20 | 0.48 |
| ▸ | CTSK | P43235 | 9/20 | 0.43 |
| ▸ | CTSB | P07858 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445093 | 0.85 | CTSS (0.47) | CTSLCTSSCTSKCTSB | |
| SCHEMBL18662370 | 0.77 | CTSS (0.54) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17275392 | 0.77 | CTSS (0.54) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7318723 | 0.74 | SMN1; SMN2 (0.52) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL11638722 | 0.74 | ALDH1A1 (0.52) | CTSLCTSSCTSKALDH1A1CYP3A4 | |
| SCHEMBL8770105 | 0.73 | CTSL (0.45) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL7201466 | 0.73 | CTSS (0.54) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7201468 | 0.73 | CTSS (0.54) | CTSLCTSSCTSKCTSB | |
| SCHEMBL13430765 | 0.73 | MAPT (0.54) | CTSLCTSSCTSBMAPK1L3MBTL1 | |
| SCHEMBL8326965 | 0.71 | CTSC (0.56) | CTSLCTSSCTSKCTSBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886647-B1 | SERINE PROTEASE INHIBITORS | AKZO NOBEL NV (NL) | 2002-07-24 | — | — | EP | disclosed |
| US-6410684-B1 | ENZYME INHIBITOR FOR USE IN THE TREATMENT OF THROMBOSIS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |
| EP-0886647-A1 | SERINE PROTEASE INHIBITORS | Akzo Nobel N.V. (NL) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997031937-A1 | SERINE PROTEASE INHIBITORS | AKZO NOBEL N.V. (NL) | 1997-09-04 | — | — | WO | disclosed |