Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445854 | 0.84 | SCN1A (0.36) | CYP3A4KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL7442088 | 0.75 | TBXAS1 (0.38) | ALDH1A1LMNAHTTSIGMAR1 | |
| SCHEMBL7448248 | 0.73 | SMN1; SMN2 (0.35) | MEN1KMT2ASLC6A2MAPTTDP1 | |
| SCHEMBL7442500 | 0.70 | TRPA1 (0.34) | MEN1KMT2ASLC6A2MAPTKDM4E | |
| SCHEMBL9134829 | 0.69 | L3MBTL1 (0.41) | MAPTCYP3A4TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9130638 | 0.68 | PPM1D (0.38) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL9540262 | 0.68 | KDM4E (0.44) | MEN1KMT2AMAPTCYP3A4TDP1 | |
| SCHEMBL9131964 | 0.66 | ALDH1A1 (0.37) | SLC6A2KDM4EPOLBALDH1A1SLC6A4 | |
| SCHEMBL7436705 | 0.66 | L3MBTL1 (0.37) | CYP3A4L3MBTL1TSHRHTT | |
| SCHEMBL7432409 | 0.65 | CASR (0.38) | KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491149-A | VIRICIDES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |