Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445854 | 0.87 | SCN1A (0.36) | CYP2D6TSHRKDM4EL3MBTL1SCN1A | |
| SCHEMBL7442088 | 0.84 | TBXAS1 (0.38) | SIGMAR1LMNAHTTGABRA1GABRG2 | |
| SCHEMBL7432982 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL7434033 | 0.76 | CCR5 (0.33) | CYP1A2TSHRL3MBTL1SCN1ASCN2A | |
| SCHEMBL7437146 | 0.73 | MEN1 (0.43) | SMN1; SMN2MAPTTSHRSIGMAR1KDM4E | |
| SCHEMBL9134829 | 0.71 | L3MBTL1 (0.41) | MAPTCYP1A2CYP2D6TSHRL3MBTL1 | |
| SCHEMBL7441666 | 0.69 | CYP1A2 (0.39) | SMN1; SMN2MAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL7436705 | 0.68 | L3MBTL1 (0.37) | CYP1A2CYP2D6TSHRHTTL3MBTL1 | |
| SCHEMBL7442500 | 0.68 | TRPA1 (0.34) | MAPTTSHRKDM4EPOLBSLC6A2 | |
| SCHEMBL7444181 | 0.66 | TSHR (0.38) | SMN1; SMN2CYP1A2CYP2D6TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491149-A | VIRICIDES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |