Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434334 | 0.91 | CCR2 (0.40) | CCR2LMNANPSR1HTTGAA | |
| SCHEMBL10994845 | 0.88 | CCR2 (0.38) | CCR2LMNATSHRNPSR1HTT | |
| SCHEMBL7437033 | 0.85 | LMNA (0.37) | LMNAHTTGAADRD2DRD4 | |
| SCHEMBL7429567 | 0.85 | ALDH1A1 (0.46) | LMNATSHRNPSR1HTTDRD2 | |
| SCHEMBL7446165 | 0.82 | TSHR (0.43) | LMNATSHRNPSR1HTTGAA | |
| SCHEMBL7495736 | 0.82 | TSHR (0.49) | LMNATSHRNPSR1HTTGAA | |
| SCHEMBL7440410 | 0.82 | ALDH1A1 (0.46) | LMNATSHRNPSR1HTTDRD2 | |
| SCHEMBL7440732 | 0.81 | MAPT (0.38) | LMNANPSR1DRD4MAPK1ALDH1A1 | |
| SCHEMBL7437941 | 0.79 | TSHR (0.43) | LMNATSHRNPSR1HTTDRD4 | |
| SCHEMBL7445153 | 0.79 | MAPT (0.36) | LMNANPSR1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |