Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446176 | 0.94 | ALDH1A1 (0.40) | LMNASOAT2SOAT1ALDH1A1GLA | |
| SCHEMBL9132381 | 0.88 | TSHR (0.44) | LMNAAKR1B1TSHRALDH1A1GLA | |
| SCHEMBL9131019 | 0.83 | TSHR (0.41) | LMNATSHRALDH1A1GLAHPGD | |
| SCHEMBL7370889 | 0.79 | SCN1A (0.44) | LMNAAKR1B1TSHRALDH1A1GLA | |
| SCHEMBL7435318 | 0.79 | SCN1A (0.38) | LMNATSHRALDH1A1GLAL3MBTL1 | |
| SCHEMBL7432308 | 0.75 | SCN1A (0.37) | TSHRALDH1A1GLAL3MBTL1HPGD | |
| SCHEMBL9133864 | 0.74 | GABRA1 (0.42) | LMNAAKR1B1SOAT2SOAT1TSHR | |
| SCHEMBL7436359 | 0.74 | SUCNR1 (0.38) | SLC6A4SLC6A3L3MBTL1CNR2 | |
| SCHEMBL8669232 | 0.73 | AKR1B1 (0.46) | LMNAAKR1B1ALDH1A1GLAL3MBTL1 | |
| SCHEMBL9131929 | 0.73 | CYP3A4 (0.41) | LMNAALDH1A1SLC6A2SLC6A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430155-A | Viricides, treatment of AIDS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-04 | — | — | US | disclosed |
| US-5294720-A | Viricides | THE DUPONT MERCK PHARMACEUTICAL CO. (US) | 1994-03-15 | — | — | US | disclosed |