SCHEMBL7432308

SCHEMBL7432308

CC(C)c1c(Cc2ccccc2)cccc1[C](Cc1ccccc1)C1CCC1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 1/20 0.37
SCN2A Q99250 1/20 0.37
SCN3A Q9NY46 1/20 0.37
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
GLA P06280 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
LDHA P00338 1/20 0.34
LDHB P07195 1/20 0.34
USP2 O75604 1/20 0.34
CYP2D6 P10635 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
FFAR1 O14842 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
RECQL P46063 1/20 0.33
HRH1 P35367 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7435318 0.96 SCN1A (0.38) SCN1ASCN2ASCN3AALDH1A1HPGD
SCHEMBL7446176 0.81 ALDH1A1 (0.40) ALDH1A1HPGDGLAUSP2CYP2D6
SCHEMBL7439021 0.79 SCN1A (0.36) SCN1ASCN2ASCN3AALDH1A1HPGD
SCHEMBL7370889 0.79 SCN1A (0.44) SCN1ASCN2ASCN3AALDH1A1HPGD
SCHEMBL7446846 0.75 TSHR (0.39) SCN1ASCN2ASCN3AALDH1A1HPGD
SCHEMBL9130434 0.75 LMNA (0.38) ALDH1A1HPGDGLAL3MBTL1TSHR
SCHEMBL7436705 0.74 L3MBTL1 (0.37) L3MBTL1LDHALDHBCYP2D6CYP2C19
SCHEMBL9131019 0.74 TSHR (0.41) ALDH1A1HPGDGLAUSP2TSHR
SCHEMBL7436359 0.73 SUCNR1 (0.38) L3MBTL1
SCHEMBL7445739 0.71 ALDH1A1 (0.39) ALDH1A1HPGDGLAL3MBTL1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5491149-A VIRICIDES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-02-13 US disclosed