Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445153 | 0.93 | MAPT (0.36) | MAPTMAPK1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL7437033 | 0.92 | LMNA (0.37) | MAPTLMNASMN1; SMN2ALDH1A1DRD4 | |
| SCHEMBL7434334 | 0.90 | CCR2 (0.40) | MAPTMAPK1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL10994263 | 0.88 | ALDH1A1 (0.41) | MAPTMAPK1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL7444058 | 0.82 | ALDH1A1 (0.44) | MAPTLMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7443888 | 0.82 | POLB (0.48) | MAPTMAPK1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL7447128 | 0.81 | RAB9A (0.52) | MAPTLMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7436396 | 0.81 | AIMP2 (0.42) | MAPTMAPK1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL7446182 | 0.81 | CCR2 (0.40) | MAPK1LMNANPSR1ALDH1A1DRD4 | |
| SCHEMBL7435451 | 0.81 | RAB9A (0.51) | MAPTLMNASMN1; SMN2NPSR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |