Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446182 | 0.91 | CCR2 (0.40) | CCR2LMNANPSR1MAPK1ALDH1A1 | |
| SCHEMBL7440732 | 0.90 | MAPT (0.38) | LMNAMAPTSMN1; SMN2NPSR1POLB | |
| SCHEMBL7445153 | 0.88 | MAPT (0.36) | LMNAMAPTSMN1; SMN2NPSR1POLB | |
| SCHEMBL11000014 | 0.87 | POLB (0.42) | LMNAMAPTSMN1; SMN2NPSR1POLB | |
| SCHEMBL7447128 | 0.86 | RAB9A (0.52) | LMNAMAPTSMN1; SMN2NPSR1POLB | |
| SCHEMBL7435451 | 0.86 | RAB9A (0.51) | LMNAMAPTSMN1; SMN2NPSR1POLB | |
| SCHEMBL7437033 | 0.85 | LMNA (0.37) | LMNAMAPTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL7433767 | 0.85 | DRD4 (0.53) | RAB9AALDH1A1 | |
| SCHEMBL7436396 | 0.84 | AIMP2 (0.42) | LMNAMAPTSMN1; SMN2NPSR1POLB | |
| SCHEMBL7436669 | 0.84 | ALDH1A1 (0.52) | LMNAMAPTSMN1; SMN2NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | claimed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |