Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL854703 | 0.86 | SHBG (0.45) | ALDH1A1HIF1AHSD17B10CYP1A2ALOX15 | |
| SCHEMBL7456234 | 0.86 | ALDH1A1 (0.58) | ALDH1A1HIF1AHSD17B10CYP1A2ALOX15 | |
| SCHEMBL14095681 | 0.79 | PDE10A (0.41) | ALDH1A1HIF1AHSD17B10CYP1A2ALOX15 | |
| SCHEMBL27611624 | 0.77 | SHBG (0.39) | ALDH1A1HIF1AHSD17B10CYP1A2ALOX15 | |
| SCHEMBL6651758 | 0.75 | ALDH1A1 (0.35) | ALDH1A1HIF1AHSD17B10CYP1A2ALOX15 | |
| SCHEMBL14095698 | 0.73 | AMY1A (0.42) | ALDH1A1HIF1AHSD17B10CYP1A2ALOX15 | |
| SCHEMBL7453601 | 0.73 | THRB (0.36) | ALDH1A1HSD17B10ALOX15SHBGKDM4E | |
| SCHEMBL12209717 | 0.72 | ALDH1A1 (0.40) | ALDH1A1HSD17B10SHBGKDM4ELMNA | |
| SCHEMBL10952937 | 0.71 | SHBG (0.37) | ALDH1A1HIF1ASHBGKDM4ELMNA | |
| SCHEMBL9800893 | 0.69 | GABRA1 (0.38) | ALDH1A1HSD17B10SHBGKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222161-A1 | AMINOPHENOL DERIVATIVES AND THE USE THEREOF IN OXIDATIVE HAIR DYES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001030743-A1 | AMINOPHENOL DERIVATIVES AND THE USE THEREOF IN OXIDATIVE HAIR DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-05-03 | — | — | WO | disclosed |