Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455832 | 0.95 | CCR2 (0.36) | PLCG1ALDH1A1MAPTHPGDSIGMAR1 | |
| SCHEMBL7462425 | 0.89 | ALDH1A1 (0.33) | ALDH1A1MAPTHPGDTDP1PKM | |
| SCHEMBL7457360 | 0.86 | PLCG1 (0.37) | PLCG1ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL7457935 | 0.84 | CCR2 (0.37) | ALDH1A1TDP1SIGMAR1CCR2CCR5 | |
| SCHEMBL7463906 | 0.83 | ALDH1A1 (0.33) | ALDH1A1MAPTHPGDTDP1SIGMAR1 | |
| SCHEMBL7456796 | 0.82 | POLB (0.34) | ALDH1A1MAPTHPGDTDP1SIGMAR1 | |
| SCHEMBL7456168 | 0.81 | SIGMAR1 (0.39) | PLCG1ALDH1A1TDP1SIGMAR1CCR5 | |
| SCHEMBL7458556 | 0.79 | CCR5 (0.33) | ALDH1A1MAPTHPGDTDP1GAA | |
| SCHEMBL7561889 | 0.78 | PKM (0.31) | PLCG1ALDH1A1MAPTHPGDPKM | |
| SCHEMBL7451770 | 0.78 | PKM (0.31) | PLCG1ALDH1A1MAPTHPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882728-B1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO CO (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |