SCHEMBL74591

SCHEMBL74591

O=c1oc2cc(O)ccc2c2oc3cc4c(cc3c12)OCO4

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.71
▸ GAA P10253 3/20 0.71
▸ HPGD P15428 3/20 0.71
▸ MEN1 O00255 3/20 0.71
▸ MAPT P10636 3/20 0.71
▸ KMT2A Q03164 3/20 0.71
▸ ESR1 P03372 3/20 0.71
▸ ESR2 Q92731 3/20 0.71
▸ RECQL P46063 2/20 0.71
▸ BLM P54132 2/20 0.71
▸ ALDH1A1 P00352 2/20 0.71
▸ GLA P06280 2/20 0.71
▸ MAOA P21397 2/20 0.71
▸ MGAM O43451 1/20 0.71
▸ NR1I2 O75469 1/20 0.71
▸ LMNA P02545 1/20 0.71
▸ POLB P06746 1/20 0.71
▸ THRB P10828 1/20 0.71
▸ CSNK2A2 P19784 1/20 0.71
▸ CSNK2B P67870 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29929471 1.00 KDM4E (0.71) KDM4EGAAHPGDMEN1MAPT
Coumestrol SCHEMBL22012 0.84 ESR2 (1.00) KDM4EGAAHPGDMEN1MAPT
Coumestrol SCHEMBL29453366 0.84 ESR2 (1.00) KDM4EGAAHPGDMEN1MAPT
SCHEMBL15870374 0.83 ESR2 (0.84) KDM4EGAAHPGDMEN1MAPT
SCHEMBL15870375 0.81 KMT2A (0.82) KDM4EGAAHPGDMEN1MAPT
SCHEMBL30629125 0.81 PKLR (0.69) KDM4EGAAHPGDMEN1MAPT
SCHEMBL26767167 0.81 PKLR (0.69) KDM4EGAAHPGDMEN1MAPT
SCHEMBL13692853 0.81 ALDH1A1 (0.51) KDM4EGAAHPGDMEN1MAPT
SCHEMBL15870371 0.77 KDM4E (0.85) KDM4EGAAHPGDMEN1MAPT
SCHEMBL234819 0.77 KDM4E (0.85) KDM4EGAAHPGDMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 — — US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 — — WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 — — WO claimed
CN-107361214-A Enzymatic hydrolysis and fermentation alfalfa meal and preparation method thereof 河南农科牧业有限公司 2017-11-21 — — CN claimed
CN-106820113-A Full clover peptide nutrient food and preparation method thereof 陕西天宝大豆食品技术研究所 2017-06-13 — — CN claimed
CN-104738065-A Medicagol-containing pesticide composition WANG BAOYAN 2015-07-01 — — CN claimed
US-20100306878-A1 HIGHLY EFFICIENT SUPPRESSOR-DEPENDENT PROTEIN EXPRESSION IN PLANTS WITH A VIRAL VECTOR BAYLOR UNIVERSITY (US) 2010-12-02 — — US claimed
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES NATURAL EXTRACTION SYS LLC (US) 2026-02-19 — — US disclosed
US-12409152-B2 Compositions and methods related to dissolved oxides Natural Extraction Systems, LLC (US) 2025-09-09 — — US disclosed
US-20250249059-A1 PLANT BASED HONEY COMPOSITION Melibio, Inc. 2025-08-07 — — US disclosed
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES Didenko, Kirill (US) 2025-07-03 — — US disclosed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US disclosed
EP-1003522-A1 A METHOD FOR PREVENTING OR CONTROLLING CATARACT THE UNIVERSITY OF SYDNEY (AU) 2000-05-31 — — EP disclosed
EP-1003470-A2 SKIN CARE COMPOSITION UNILEVER PLC (GB) 2000-05-31 — — EP disclosed
US-6030620-A FOR DELIVERING PHYTOESTROGEN TO HUMAN SKIN CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 2000-02-29 — — US disclosed
WO-1999004748-A2 SKIN CARE COMPOSITION UNILEVER PLC (GB) 1999-02-04 — — WO disclosed
WO-1998026784-A1 A METHOD FOR PREVENTING OR CONTROLLING CATARACT THE UNIVERSITY OF SYDNEY (AU) 1998-06-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB KDM4E 4637/4885GAA 98/4885HPGD 533/4885
US-12409152-B2 Compositions and methods related to dissolved oxides PRKG2, PRKG1, CIT KDM4E 4365/4885GAA 2468/4885HPGD 317/4885
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES ACE2, FURIN, SARS1 KDM4E 2815/4885GAA 1541/4885HPGD 2020/4885
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES SCO2, CNR2, CNR1 KDM4E 3795/4885GAA 4777/4885HPGD 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback