Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.55 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472478 | 0.89 | CCR2 (0.50) | MAPK8MAPK9HDAC6MAPTHDAC1 | |
| SCHEMBL7466124 | 0.88 | CMA1 (0.46) | MAPK8MAPK9HDAC6MAPTHDAC1 | |
| SCHEMBL7461329 | 0.88 | CMA1 (0.46) | MAPK8MAPK9HDAC6MAPTHDAC1 | |
| SCHEMBL4456863 | 0.88 | GABRA5 (0.53) | MAPK8MAPK9CMA1LMNASMN1; SMN2 | |
| SCHEMBL7468517 | 0.88 | HDAC6 (0.52) | MAPK8MAPK9HDAC6MAPTHDAC1 | |
| SCHEMBL7462072 | 0.87 | MAPK8 (0.47) | MAPK8MAPK9HDAC6MAPTHDAC1 | |
| SCHEMBL7470273 | 0.86 | CCR2 (0.47) | MAPK8MAPK9HDAC6MAPTHDAC1 | |
| SCHEMBL7469901 | 0.85 | CMA1 (0.44) | MAPK8MAPK9HDAC6MAPTHDAC1 | |
| SCHEMBL7459226 | 0.85 | PARG (0.44) | MAPK8MAPK9HDAC6HDAC1HDAC8 | |
| SCHEMBL7462052 | 0.85 | KMT2A (0.47) | MAPK8MAPK9HDAC6MAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |