Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 4/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470273 | 0.90 | CCR2 (0.47) | PARGCMA1HDAC6HDAC1HDAC8 | |
| SCHEMBL7461329 | 0.86 | CMA1 (0.46) | PARGCMA1HDAC6HDAC1HDAC8 | |
| SCHEMBL7460713 | 0.85 | MAPK8 (0.55) | CMA1HDAC6HDAC1HDAC8SRC | |
| SCHEMBL7466124 | 0.84 | CMA1 (0.46) | PARGCMA1HDAC6HDAC1HDAC8 | |
| SCHEMBL7462052 | 0.83 | KMT2A (0.47) | PARGCMA1HDAC6HDAC1HDAC8 | |
| SCHEMBL7468517 | 0.83 | HDAC6 (0.52) | CMA1HDAC6HDAC1HDAC8MAPK8 | |
| SCHEMBL7463851 | 0.82 | NOX4 (0.46) | PARGCMA1MAPK8MAPK9MEN1 | |
| Iodide SCHEMBL7467165 | 0.79 | CMA1 (0.42) | PARGCMA1HDAC6HDAC1HDAC8 | |
| SCHEMBL4456863 | 0.79 | GABRA5 (0.53) | PARGCMA1SRCMAPK8MAPK9 | |
| SCHEMBL7559676 | 0.79 | HDAC6 (0.43) | PARGCMA1HDAC6HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |