Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 6/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466206 | 0.91 | MAPK14 (0.36) | MAOBHIF1APPARGPPARA | |
| SCHEMBL7467539 | 0.88 | MAOB (0.46) | MAOBHIF1A | |
| SCHEMBL8544631 | 0.85 | MAPK14 (0.37) | MAOBHIF1AMAPT | |
| SCHEMBL7465135 | 0.84 | MAOB (0.43) | MAOBHIF1ASLC6A5FFAR1PPARG | |
| SCHEMBL7499090 | 0.84 | HIF1A (0.47) | MAOBHIF1ASLC6A5FFAR1PPARG | |
| SCHEMBL7464106 | 0.81 | HIF1A (0.35) | HIF1AALDH1A1POLBMAPT | |
| SCHEMBL7470381 | 0.79 | HTR2A (0.34) | HIF1AFFAR1 | |
| SCHEMBL8540309 | 0.79 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL7494028 | 0.79 | MAPK14 (0.39) | HIF1AMAPTRAB9A | |
| SCHEMBL7503269 | 0.78 | MAPT (0.38) | HIF1AALDH1A1POLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-B1 | PESTICIDES | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |