Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.32 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.32 |
| ▸ | FNTA | P49354 | 2/20 | 0.31 |
| ▸ | FNTB | P49356 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 2/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464106 | 0.92 | HIF1A (0.35) | CYP1A2CYP2D6CYP2C19HIF1AKMT2A | |
| SCHEMBL7466206 | 0.87 | MAPK14 (0.36) | FNTAFNTBHIF1AKMT2A | |
| SCHEMBL8544631 | 0.87 | MAPK14 (0.37) | HIF1ARAF1 | |
| SCHEMBL7469946 | 0.83 | ALDH1A1 (0.35) | HTR2ASLC6A4KCNH2FFAR1CYP1A2 | |
| SCHEMBL8540309 | 0.82 | ALDH1A1 (0.36) | KMT2A | |
| SCHEMBL7498528 | 0.82 | HIF1A (0.39) | HTR2ASLC6A4KCNH2FFAR1CYP1A2 | |
| SCHEMBL7494028 | 0.80 | MAPK14 (0.39) | HIF1ARAF1 | |
| SCHEMBL7467428 | 0.79 | MAOB (0.43) | FFAR1HIF1A | |
| SCHEMBL7467539 | 0.79 | MAOB (0.46) | HIF1AKMT2A | |
| SCHEMBL7503269 | 0.77 | MAPT (0.38) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-B1 | PESTICIDES | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |