Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566236 | 0.84 | LMNA (0.41) | S1PR2MAPTTP53ALDH1A1GAA | |
| SCHEMBL7467388 | 0.80 | PSEN1 (0.42) | ALDH1A1HSD17B10HDAC1HDAC8HDAC6 | |
| SCHEMBL7472833 | 0.78 | MAPT (0.48) | MAPTTP53ALDH1A1GAAPOLB | |
| SCHEMBL7472667 | 0.78 | TP53 (0.42) | RXFP1MAPTTP53POLB | |
| SCHEMBL7465177 | 0.77 | S1PR2 (0.49) | S1PR2RXFP1MAPTTP53ALDH1A1 | |
| SCHEMBL7468006 | 0.77 | MAPT (0.46) | S1PR2MAPTTP53ALDH1A1GAA | |
| SCHEMBL7463377 | 0.76 | TSHR (0.42) | RXFP1MAPTTP53ALDH1A1GAA | |
| SCHEMBL7472701 | 0.76 | PSEN1 (0.42) | ALDH1A1LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL7465215 | 0.76 | CMA1 (0.35) | MAPTALDH1A1HSD17B10 | |
| SCHEMBL7563746 | 0.76 | MAPT (0.49) | S1PR2RXFP1MAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |