Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481618 | 1.00 | RAB9A (0.38) | RAB9AKMT2AKIF11KDM4ELDHA | |
| SCHEMBL7465381 | 0.86 | MEN1 (0.33) | RAB9AKMT2AKDM4EGSK3BDYRK1A | |
| SCHEMBL27480827 | 0.85 | PKN1 (0.32) | RAB9AKIF11KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7474017 | 0.85 | PKN1 (0.32) | RAB9AKIF11KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7479201 | 0.80 | NISCH (0.35) | RAB9AKMT2AALDH1A1NPC1MAPT | |
| SCHEMBL7472105 | 0.80 | GAA (0.39) | KDM4EGSK3BDYRK1AALDH1A1NPY5R | |
| SCHEMBL7471032 | 0.78 | ALPL (0.36) | RAB9AKMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL7472583 | 0.78 | TNKS (0.32) | RAB9AKMT2AKDM4EDYRK1AALDH1A1 | |
| SCHEMBL7472388 | 0.78 | PDGFRB (0.41) | ALDH1A1CYP2A6CYP1A2 | |
| SCHEMBL7473052 | 0.76 | KDM4E (0.40) | RAB9AKMT2AKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967207-B1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-09-11 | — | — | EP | disclosed |
| EP-0967207-A1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-12-29 | — | — | EP | disclosed |