Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | STK3 | Q13188 | 2/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471032 | 0.84 | ALPL (0.36) | GAAKDM4EALDH1A1NPBWR1MGAM | |
| SCHEMBL27552770 | 0.84 | ALPL (0.36) | GAAKDM4EALDH1A1NPBWR1MGAM | |
| SCHEMBL7465381 | 0.84 | MEN1 (0.33) | KDM4EALDH1A1NPBWR1NPY5RMAP4K4 | |
| SCHEMBL7470009 | 0.81 | CYP11B1 (0.35) | KDM4EALDH1A1GFERPDGFRB | |
| SCHEMBL27481618 | 0.80 | RAB9A (0.38) | KDM4EALDH1A1NPY5RGSK3BDYRK1A | |
| SCHEMBL7472593 | 0.80 | RAB9A (0.38) | KDM4EALDH1A1NPY5RGSK3BDYRK1A | |
| SCHEMBL27480827 | 0.78 | PKN1 (0.32) | GAAKDM4EALDH1A1MGAMSI | |
| SCHEMBL7479201 | 0.78 | NISCH (0.35) | ALDH1A1NPBWR1 | |
| SCHEMBL7474017 | 0.78 | PKN1 (0.32) | GAAKDM4EALDH1A1MGAMSI | |
| SCHEMBL7467570 | 0.77 | ALDH1A1 (0.36) | GAAKDM4EALDH1A1NPBWR1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1153766-C | Nitroketone compound, its preparing process and pharmaceutical composition containing same | ɪά��ʵ���� | 2004-06-16 | — | — | CN | disclosed |
| EP-0967207-B1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-6034250-A | ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 2000-03-07 | — | — | US | disclosed |
| EP-0967207-A1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-12-29 | — | — | EP | disclosed |