Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | PARG | Q86W56 | 2/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460713 | 0.85 | MAPK8 (0.55) | ALDH1A1CMA1MEN1GAAKMT2A | |
| SCHEMBL7466124 | 0.83 | CMA1 (0.46) | PARGCMA1GABRA1GABRA5GRIN1 | |
| SCHEMBL7463810 | 0.81 | SMN1; SMN2 (0.45) | ALDH1A1MEN1KMT2ALMNAPSEN1 | |
| SCHEMBL4456863 | 0.80 | GABRA5 (0.53) | PARGCMA1GABRA1GABRA5KMT2A | |
| SCHEMBL7469901 | 0.80 | CMA1 (0.44) | ALDH1A1PARGCMA1GAALMNA | |
| SCHEMBL7461329 | 0.78 | CMA1 (0.46) | ALDH1A1PARGCMA1MEN1KMT2A | |
| SCHEMBL7463851 | 0.78 | NOX4 (0.46) | ALDH1A1PARGCMA1MEN1GAA | |
| SCHEMBL7459226 | 0.76 | PARG (0.44) | ALDH1A1PARGCMA1MEN1KMT2A | |
| SCHEMBL7468517 | 0.76 | HDAC6 (0.52) | CMA1MEN1KMT2AMAPK8MAPK9 | |
| SCHEMBL7462052 | 0.76 | KMT2A (0.47) | ALDH1A1PARGCMA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |