SCHEMBL7468587

SCHEMBL7468587

CCc1ccc(-c2nc(/C=[N+](\[O-])C(C)(C)C)c[nH]2)o1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15330895 0.78 CHRM2 (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL27481619 0.76 ALDH1A1 (0.39)
SCHEMBL7476978 0.76 ALDH1A1 (0.39)
SCHEMBL8056565 0.75 ADRA2A (0.44)
SCHEMBL7465381 0.72 MEN1 (0.33)
SCHEMBL7474017 0.71 PKN1 (0.32)
SCHEMBL7479201 0.71 NISCH (0.35)
SCHEMBL7471772 0.71 TMIGD3 (0.33)
SCHEMBL7471032 0.70 ALPL (0.36)
SCHEMBL7472583 0.70 TNKS (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1153766-C Nitroketone compound, its preparing process and pharmaceutical composition containing same ɪά��ʵ���� 2004-06-16 CN disclosed
EP-0967207-B1 Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2002-09-11 EP disclosed
US-6034250-A ANTIOXIDANTS ADIR ET COMPAGNIE (FR) 2000-03-07 US disclosed
EP-0967207-A1 Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1999-12-29 EP disclosed