Sugi Predict

Sugi Predict / Compounds / SCHEMBL7469811

SCHEMBL7469811

SCHEMBL7469811

CCC(=O)NC(C)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.65
▸ MEN1 O00255 2/20 0.64
▸ KMT2A Q03164 2/20 0.64
▸ GPR139 Q6DWJ6 2/20 0.61
▸ ALDH1A1 P00352 2/20 0.61
▸ HPGD P15428 1/20 0.61
▸ NPC1 O15118 1/20 0.59
▸ CYP3A4 P08684 1/20 0.59
▸ CYP2D6 P10635 1/20 0.59
▸ CYP2C9 P11712 1/20 0.59
▸ CYP2C19 P33261 1/20 0.59
▸ CASR P41180 1/20 0.58
▸ PKM P14618 1/20 0.58
▸ POLB P06746 2/20 0.57
▸ GAA P10253 1/20 0.56
▸ HTT P42858 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ HSD17B10 Q99714 1/20 0.56
▸ CTDSP1 Q9GZU7 1/20 0.56
▸ KDM4E B2RXH2 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12975495 1.00 MAPT (0.65) MAPTMEN1KMT2AGPR139ALDH1A1
SCHEMBL12975787 1.00 MAPT (0.65) MAPTMEN1KMT2AGPR139ALDH1A1
SCHEMBL15571840 0.87 LMNA (0.67) MAPTMEN1KMT2AGPR139ALDH1A1
SCHEMBL17291601 0.87 LMNA (0.67) MAPTMEN1KMT2AGPR139ALDH1A1
SCHEMBL15571273 0.87 LMNA (0.67) MAPTMEN1KMT2AGPR139ALDH1A1
SCHEMBL16975095 0.85 MAPT (0.71) MAPTMEN1KMT2AGPR139ALDH1A1
SCHEMBL18241727 0.85 MAPT (0.71) MAPTMEN1KMT2AGPR139ALDH1A1
SCHEMBL6083488 0.85 GPR139 (0.66) MAPTMEN1KMT2AGPR139ALDH1A1
SCHEMBL19285674 0.85 GPR139 (0.66) MAPTMEN1KMT2AGPR139ALDH1A1
SCHEMBL7204764 0.85 MAPT (0.65) MAPTMEN1KMT2AGPR139ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1244653-A1 NON PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 2002-10-02 — — EP claimed
WO-2001046176-A2 NON PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 2001-06-28 — — WO claimed
US-12564547-B2 Compositions, formulations, and methods for skin treatment ODDITY LABS, LLC (US) 2026-03-03 — — US disclosed
US-20230240960-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT ODDITY LABS, LLC 2023-08-03 — — US disclosed
US-20230240960-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT ODDITY LABS, LLC 2023-08-03 — — US disclosed
US-20230240960-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT ODDITY LABS, LLC 2023-08-03 — — US disclosed
WO-2023133240-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT REVELA, INC. (US) 2023-07-13 — — WO disclosed
WO-2022090284-A1 EUROPIUM(III) COMPLEXES AS PH SENSORS CISBIO BIOASSAYS (FR) 2022-05-05 — — WO disclosed
US-20210032265-A1 COMPOSITIONS AND METHODS OF MODULATING 15-PGDH ACTIVITY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-02-04 — — US disclosed
CN-109071503-A Compound and application thereof for inhibiting cyclophilin 默克专利有限公司 2018-12-21 — — CN disclosed
US-8293757-B2 5-(4-(haloalkoxy)phenyl) pyrimidine-2-amine compounds and compositions as kinase inhibitors IRM LLC (BM) 2012-10-23 — — US disclosed
US-20070149538-A1 Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors IRM LLC (BM) 2007-06-28 — — US disclosed
EP-1090907-B1 A process for the production of amides from amines COUNCIL SCIENT IND RES (IN) 2002-12-04 — — EP disclosed
EP-1244653-A1 NON PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 2002-10-02 — — EP disclosed
WO-2001046176-A2 NON PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 2001-06-28 — — WO disclosed
EP-1090907-A1 A process for the production of amides from amines COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2001-04-11 — — EP disclosed
US-5556874-A ENZYME INHIBITORS AS ANTICARCINOGENIC AGENTS WARNER LAMBERT COMPANY (US) 1996-09-17 — — US disclosed
US-5464861-A Anticarcinogenic agents WARNER-LAMBERT (US) 1995-11-07 — — US disclosed
EP-0654024-A1 2-THIOINDOLES (SELENOINDOLES) AND RELATED DISULFIDES (SELENIDES) WHICH INHIBIT PROTEIN TYROSINE KINASES AND WHICH HAVE ANTITUMOR PROPERTIES WARNER-LAMBERT COMPANY (US) 1995-05-24 — — EP disclosed
WO-1994003427-A1 2-THIOINDOLES (SELENOINDOLES) AND RELATED DISULFIDES (SELENIDES) WHICH INHIBIT PROTEIN TYROSINE KINASES AND WHICH HAVE ANTITUMOR PROPERTIES WARNER-LAMBERT COMPANY (US) 1994-02-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240960-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT CUTA, COL14A1, DSG1 MAPT 404/4885MEN1 2544/4885KMT2A 2123/4885
US-12564547-B2 Compositions, formulations, and methods for skin treatment MCOLN1, H1-0, APOL1 MAPT 3212/4885MEN1 2800/4885KMT2A 2155/4885
US-20210032265-A1 COMPOSITIONS AND METHODS OF MODULATING 15-PGDH ACTIVITY PTGS1, HPGD, PTGIS MAPT 4311/4885MEN1 4530/4885KMT2A 4177/4885
US-20070149538-A1 Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors KIT, PRKCH, PRKCE MAPT 4217/4885MEN1 2421/4885KMT2A 646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.