⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475246 | 0.78 | METAP2 (0.37) | — | |
| SCHEMBL7465381 | 0.74 | MEN1 (0.33) | — | |
| SCHEMBL7474017 | 0.73 | PKN1 (0.32) | — | |
| SCHEMBL7479201 | 0.73 | NISCH (0.35) | — | |
| SCHEMBL2928851 | 0.72 | — | — | |
| SCHEMBL27552770 | 0.72 | ALPL (0.36) | — | |
| SCHEMBL7472583 | 0.72 | TNKS (0.32) | — | |
| SCHEMBL7471032 | 0.72 | ALPL (0.36) | — | |
| SCHEMBL7471435 | 0.72 | MEN1 (0.39) | — | |
| SCHEMBL7477061 | 0.71 | KDM4E (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967207-B1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-6034250-A | ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 2000-03-07 | — | — | US | disclosed |
| EP-0967207-A1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-12-29 | — | — | EP | disclosed |