Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465381 | 0.77 | MEN1 (0.33) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL15330068 | 0.76 | KDM4E (0.44) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL7479201 | 0.73 | NISCH (0.35) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7474017 | 0.73 | PKN1 (0.32) | NPC1RAB9AKDM4ENPSR1ALDH1A1 | |
| SCHEMBL7472593 | 0.73 | RAB9A (0.38) | KMT2ANPC1RAB9AKDM4ENPSR1 | |
| SCHEMBL7475246 | 0.73 | METAP2 (0.37) | KMT2ANPC1RAB9AKDM4ENPSR1 | |
| SCHEMBL27481619 | 0.73 | ALDH1A1 (0.39) | MEN1KMT2AKDM4ERECQLALDH1A1 | |
| SCHEMBL7476978 | 0.73 | ALDH1A1 (0.39) | MEN1KMT2AKDM4ERECQLALDH1A1 | |
| SCHEMBL7467570 | 0.73 | ALDH1A1 (0.36) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL7472583 | 0.72 | TNKS (0.32) | MEN1KMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967207-B1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-6034250-A | ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 2000-03-07 | — | — | US | disclosed |
| EP-0967207-A1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-12-29 | — | — | EP | disclosed |