Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491544 | 0.79 | TDP1 (0.49) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL902241 | 0.77 | ALOX15 (0.53) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL8894450 | 0.75 | ALDH1A1 (0.30) | ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL1803317 | 0.71 | KDM4E (0.46) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL11850746 | 0.71 | KMT2A (0.39) | ALDH1A1HPGDKMT2AL3MBTL1POLB | |
| SCHEMBL1985491 | 0.71 | GPR174 (0.40) | ALDH1A1MEN1GAAMAPTKMT2A | |
| SCHEMBL584941 | 0.71 | — | — | |
| SCHEMBL6238419 | 0.71 | JAK2 (0.33) | ALDH1A1GAAMAPTHPGD | |
| SCHEMBL7476929 | 0.70 | HPGD (0.44) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL9695964 | 0.69 | PTGDR2 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |