Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27464538 | 1.00 | PDGFRB (0.32) | PDGFRBCDK8LRRK2USP2ALDH1A1 | |
| SCHEMBL27480827 | 0.82 | PKN1 (0.32) | ALDH1A1 | |
| SCHEMBL7474017 | 0.82 | PKN1 (0.32) | ALDH1A1 | |
| SCHEMBL7465381 | 0.81 | MEN1 (0.33) | CDK8LRRK2ALDH1A1MEN1KMT2A | |
| SCHEMBL7479201 | 0.80 | NISCH (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL27552770 | 0.78 | ALPL (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7471032 | 0.78 | ALPL (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7472583 | 0.78 | TNKS (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7473052 | 0.76 | KDM4E (0.40) | PDGFRBALDH1A1PKMMEN1GFER | |
| SCHEMBL7472593 | 0.76 | RAB9A (0.38) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967207-B1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-6034250-A | ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 2000-03-07 | — | — | US | disclosed |
| EP-0967207-A1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-12-29 | — | — | EP | disclosed |