Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469467 | 0.88 | MAPK8 (0.35) | ALDH1A1KDM4EHCRTR1HCRTR2 | |
| SCHEMBL7468740 | 0.82 | CYP1A2 (0.43) | ALDH1A1KDM4ENPSR1MAPT | |
| SCHEMBL382601 | 0.80 | OPRK1 (0.41) | ALDH1A1OPRK1KDM4EHRH3MAPT | |
| SCHEMBL7474484 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4ENPSR1MAPT | |
| SCHEMBL7473696 | 0.78 | OPRK1 (0.42) | ALDH1A1OPRK1KDM4EHCRTR1HCRTR2 | |
| SCHEMBL7462635 | 0.74 | RORC (0.38) | ALDH1A1KDM4EMAPT | |
| SCHEMBL7051584 | 0.72 | KDM4E (0.37) | KDM4EHCRTR1MAPT | |
| SCHEMBL7466043 | 0.71 | OPRK1 (0.43) | ALDH1A1OPRK1KDM4ENPSR1MAPT | |
| SCHEMBL7468832 | 0.70 | TDP1 (0.39) | ALDH1A1KDM4EMAPTCNR2 | |
| SCHEMBL7054704 | 0.69 | ALDH1A1 (0.45) | ALDH1A1OPRK1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |