Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481736 | 0.70 | KMT2A (0.34) | KMT2AFKBP1AMEN1 | |
| SCHEMBL11016507 | 0.61 | HTR2A (0.58) | KMT2AHTR2AHTR2BHTR2CAOC3 | |
| SCHEMBL10959061 | 0.60 | TUBB4A (0.56) | KMT2AHTR2AHTR2BHTR2CAOC3 | |
| SCHEMBL2930056 | 0.58 | HTR2A (0.59) | KMT2AHTR2AHTR2BHTR2CAOC3 | |
| SCHEMBL5568951 | 0.57 | PTGS2 (0.63) | KMT2AHTR2AHTR2BHTR2CAOC3 | |
| SCHEMBL9306683 | 0.56 | AOC3 (0.64) | HTR2AHTR2BHTR2CAOC3 | |
| SCHEMBL5514786 | 0.56 | PTGS2 (0.61) | HTR2AHTR2BHTR2CAOC3 | |
| SCHEMBL7478153 | 0.56 | L3MBTL1 (0.43) | KMT2AMEN1 | |
| SCHEMBL8330517 | 0.56 | ALDH1A1 (0.48) | KMT2AHTR2AHTR2BHTR2CMEN1 | |
| SCHEMBL7424861 | 0.55 | HTR2A (0.69) | HTR2AHTR2BHTR2CAOC3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865281-A4 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LAB (US) | 1999-07-28 | — | — | EP | disclosed |
| EP-0865281-A1 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LABORATORIES, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997021437-A1 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LABORATORIES, INC. (DE) | 1997-06-19 | — | — | WO | disclosed |